scientific research
In the 1930s, Elviem's interest turned to vitamins, which was an topic for many biochemists. At that time, the structure of vitamins was gradually disclosed by chemical analysis, and the molecular structure of the coenzyme was also the same. As Ogil-Kyle, and Warbe, others have confirmed Harden's coenzyme and closely related co-related coenzymes containing nicotinic acid as their molecular structure. Early 1912 Feng Ke has separated from rice bran. However, Feng Ke studied the effect of niacin on the foot of the foot and did not succeed. However, in this important enzyme molecule in such an important activity of the body, niacin is interested in it. Since Feng Ke's discovery, relying on Goride's research work has been sufficiently confirmed that rough skin disease is also a nutrient deficiency. Feng Ke himself also proposes brown skin diseases may be a nutrient lacking. So would so nicothenic acid will benefit? In 1937, El Viem studied with a dog with black tongue, black tongue is a disease similar to a rough skin disease, he feeds a dog 30 mg of nicotinic acid. There is a significant improvement in the treatment after administration, and the diseased dog is completed after further feeding. The significance of this study is far from proves nicotinic acid being a vitamin and anti-rough skin. According to biochemical knowledge, people have been able to determine that rough skin disease is a group of symptoms, which are caused by normal function of certain enzymes. Lost normal function is to utilize those enzymes containing niacin in the structure. The body cannot produce niacin from a simple compound, but must be supplied by food containing niacin. This establishment of the theoretical basis for vitamin requirements. Since then, many vitamin B are associated with specific coenzymes; for example, it is found that the panto acid is part of LiPman's coenzyme A, while Oreal has discovered riboflavin (vitamin B2) as part of other coenzymes. El Viem has been studied for trace minerals such as zinc and cobalt. The activities in this research area have reached a climax at the work of Fox after ten years. These minerals are also essential for life, and their need is tiny, and they are also part of the enzyme like vitamins.
